Grey turners sign takes 2448 hours to develop, and can predict a severe attack of acute pancreatitis. Cullen s sign is superficial edema and bruising in the subcutaneous fatty tissue around the umbilicus it is named for gynecologist thomas stephen cullen 18691953, who first described the sign in ruptured ectopic pregnancy in 1916 this sign takes 2448 hours to appear and can predict acute pancreatitis, with mortality rising from 810% to 40%. Images in clinical medicine from the new england journal of medicine cullen s and grey turner s signs in acute pancreatitis. Images in clinical medicine from the new england journal of medicine cullens and grey turners signs in acute pancreatitis. Grey turners sign in acute necrotizing pancreatitis. Grey turner s sign refers to bruising of the flanks, the part of the body between the last rib and the top of the hip. Acute pancreatitis affects about 50,000 80,000 americans each year. Wright, do, mph and george grey turner, mbbs, respectively, are signs of abdominal wall hemorrhage and are generally associated with acute pancreatitis. Pancreatitis is an uncommon disease characterized by inflammation of the pancreas. Jul 08, 2016 dr william english specialist trainee in general surgery uk image by herbert l. It may be accompanied by grey turners sign bruising of the flank, which may then be indicative of pancreatic necrosis with retroperitoneal or intraabdominal bleeding. Jul, 2014 grey turners sign was described by a british surgeon for the first time in 1920 in a patient of acute pancreatitis.
The patient received supportive care with fluid hydration, pain medication, and bowel rest. Dr william english specialist trainee in general surgery uk image by herbert l. Cullens and grey turners signs in acute pancreatitis by. Pancreatitis aguda trastornos gastrointestinales manual. Grey turner s sign was described by a british surgeon for the first time in 1920 in a patient of acute pancreatitis. It is a condition that arises suddenly and may be quite severe, although patients usually have a complet e recovery from an acute attack. Cullen sign and grey turner sign revisited william f.
Physical examination at the time of the transfer revealed jaundice, with an. Bruetman1 armand trousseau 18011867, his history and the signs of hypocalcemia armand trousseau 18011867 was born in tours, france on october 14. This sign is nonspecific for acute pancreatitis and has been described in retroperitoneal hemorrhage secondary to hepatocellular carcinoma, trauma, perirenal hematoma, and portal hypertension 2,3. These observations help confirm the precise anatomic pathways by which the extravasated pancreatic enzymes and their effects lead to these cutaneous discolorations. His condition deteriorated, and he was transferred to the intensive care unit 2 days after hospital admission. A video demonstrating cullen s sign seen in acute pancreatitis with accompanying explaination and self assessment questions. Cullens and grey turners signs in acute pancreatitis nejm. Grey turner s sign takes 2448 hours to develop, and can predict a severe attack of acute pancreatitis. This sign takes 2448 hours to appear and can predict acute pancreatitis, with mortality rising from 810% to 40%. Four patients with acute pancreatitis presenting with grey turner s sign or cullen s sign have been studied by computed tomography ct. However, the research from which these signs arose was documented long before cullen and grey turner made their contributions.
1507 495 1075 1111 1662 374 1298 1139 1279 778 1692 133 1381 99 79 958 961 1435 1099 1343 313 1521 1255 201 1148 571 279 839 1385 1336 679